This is happened three times now. The guides appear on the screen is white even though there specified color in preferences still the default. The white areas on the screen such as the page and pasteboard color is light yellow.

The first time resetting the preferences fixed it. The second time it did not but re-profiling the monitor did. The third time neither fixed it and after rebooting InDesign gave me the "configuration error", "error 16".

I followed the instructions for this error that I found here:
https://helpx.adobe.com/creative-cloud/kb/configuration-error.html#mac_os

Since this happened InDesign seems to be less stable and before and has crashed on me several times when I was quitting the program.

The next time the error occurs I will attempt to get a screenshot.

Mac Pro, OSX 10.11.6, InDesign 12.0.0.81 (And no I will not update InDesign to see if this fixes the issue)

VERSIONS
Windows 7, CC 2015.4 and CC 2017.0
Windows 10, CC 2015.4 and CC 2017.0
macOS 10.12, CC 2015.4
even CS6 versions are affected...

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STEPS TO REPRODUCE
1. Create an InDesign document with several pages
2. Define the text frame options with two columns
3. Link all frames and fill with placeholder text
4. Create a new paragraph style with the option "span columns" (e.g. title)
5. Define several parts of the layout with the new paragraph style
6. Edit some text near the paragraph style
--> the performance while typing is very very bad!!!

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EXPECTED RESULT
InDesign and InCopy should still be usable when a layout file was built using either "span column" or "split column" (e.g. using a paragraph style > "Span Columns").

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ACTUAL RESULT
Very bad performance - working is NOT possible anymore

Version - Adobe Indesign CC
2015.3 Release
11.3.0.34 Build
operating on Mac OS X El Capitan, Version 10.11

Steps to reproduce issues:

Create a new document with a double-page spread in Indesign.
Import four images into document and arrange on spread.

Import a shape into Indesign that will be assigned as a pop up box that will appear above Image 1 when rolled over, and place shape next to Image 1.
Place some text (e.g. "Image credit') on top of shape and group text with shape.
Open Buttons and Forms dialogue box:
- Convert group to a button.
- Set 'Name' as: Pop up 1.
- Check box to turn 'Hidden until triggered' on.

Select Image 1 which will be the trigger image for Pop up 1.
Open Buttons and Forms dialogue box:
- Convert Image 1 to a button.
- Set 'Name' as: Image 1
- Select 'Event: On Roll Over'.
- Add a new action: 'Show/Hide Buttons and Forms'.
- Set 'Visibility': select Pop-up 1 from list and set visibility as 'show'. Set visibility for 'Image 1' itself to 'ignore'.
- Appearance: [Normal] is selected.

- Select "Event: On Roll Off'.
- Add a new action: 'Show/Hide Buttons and Forms'.
- Set 'Visibility': select Pop-up 1 from list and set visibility as 'hide'. Set visibility for 'Image 1' itself to 'ignore'.
- Appearance: [Normal] is selected.

Repeat above steps for Images 2, 3 and 4.
Export as interactive PDF.

Actual result: 3 out of four of the images will trigger a pop up box when rolled over in the Interactive PDF as exported from Indesign. The fourth image does not trigger its assigned pop up box. The settings are exactly the same for all four images and pop up boxes. The shapes for the pop-up boxes are each imported separately, not copied and pasted. Sometimes none display, sometimes all, sometimes half. I cannot depend on this feature to work correctly.

Expected Result: Each of the four images will trigger a hidden separate pop up box for its corresponding image when rolled over and the pop-up box will revert to being hidden when the image is rolled off.