My agency has to do a lot of remediation to our files to meet accessibility requirements. Currently we use the layers panel to arrange objects on the page so that the reading order makes sense when the PDFs are read using assistive software. With files set up in spreads, all items on the spread are considered in the reading order despite the final PDF being output as single pages. It would be nice if the layers panel could be configured to address one page at a time (vs. two pages, as it is now). For simple projects, the spread approach works fine, but as projects become more complex and with the addition of more pages, this becomes extremely time consuming to remediate.